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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Ricanourced farmers' vegetables2.

This product does not require a doctor's prescription; it is an acceptable interaction.3. Other Drug-Food Interactions:

  • aila, marijuana
  • methoxyflurane
  • quinidine, quinidine (brand name Proquin)
  • rifabutin, rifampicin
  • cefipentas aripy, cefuroxime (brand name Cefixime)
  • lisinopril
  • furosemide

Other drug-food interactions may be caused by different medications. Seek guidance from your doctor or pharmacist.

C.

Similar to nitrates and alpha-blockers, Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects.

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Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) that helps restore sexual function after men have sexual intercourse. This medication, known for its ability to restore sexual function and improve erectile function, has earned its reputation for treating ED.

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The drug is used to treat erectile dysfunction in men, which is characterized by the inability to achieve or maintain an erection sufficient for sexual activity. It works by relaxing the smooth muscles in the penile region, which in turn improves blood flow and enhances sexual arousal.

The drug is also used to treat pulmonary arterial hypertension (PAH), a condition that results in high blood pressure in the arteries in the lungs. This increases the force of the blood flow to the lungs, which reduces the workload on the heart and consequently improves the quality of life.

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The most commonly reported side effects of Viagra are headache, dizziness, flushing, and nasal congestion. These side effects usually subside within a few hours.

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